. 2014 Jul 14;8(3):836–840. doi: 10.3892/etm.2014.1843

Table I.

The effects of fasudil on glucose metabolism parameters in rats at week 24.

Group	Control	Diabetic	DM+fas
FBG (mmol/l)	5.65±0.23	19.57±0.71^a	20.10±0.61^a,^b
FINS (mU/l)	33.95±2.51	52.53±5.47^a	47.08±2.90^a,^b
HOMA-IR	8.50±0.64	44.13±3.25^a	41.93±2.51^a,^b

Differences among the three groups were assessed using one-way analysis of variance. The levels of FBG, FINS and HOMA-IR in the diabetic and the DM+fas groups were significantly increased compared to those in the control group, while no difference was identified between the diabetic group and the DM+fas group.

P<0.05 compared with the control group,

P>0.05 compared with the diabetic group. The number of rats in each group was six. Data are presented as the mean ± standard deviation.

DM+fas: diabetic rats treated with fasudil; FBG, fasting blood glucose; FINS, fasting insulin; HOMA-IR, homeostasis model assessment for insulin resistance, calculated as FBG (mmol/l) x FINS (mU/l)/22.5.