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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: J Neuroimmunol. 2014 Jun 7;273(0):31–41. doi: 10.1016/j.jneuroim.2014.05.015

Figure 3. AS101 inhibits activation of Akt, Stat3, and RORγt, but upregulates activation of ERK1/2.

Figure 3

CD4+ T cell were cultured under Th17 polarization condition (TGF-β, IL-6, and IL-23) with or without different dosage of AS101 as Fig. 1. Western blots were used to measure the activation of STAT3, AKT, RORγt, and ERK1/2 in Th17 cell lysates. GAPDH represents a loading control. The data are representative of 3 similar experiments.