Figure 9. AS101 reduces the inflammatory cytokine production by mononuclear cells in spinal cords.
At 19 day of postimmunization, mononuclear cells were isolated from spinal cords of EAE mice treated with PBS and AS101 as described in materials and methods. Real-time PCR and flow cytometry were used to quantify the inflammatory cytokine mRNA (A) and protein expression (B). One of two repeat experiments is shown. *, p< 0.05, ** p< 0.01.