Table 2.
Strain/Stage | Controla (mean;sd) | Mutant (mean;sd) | % change | |
---|---|---|---|---|
Efnb2 CKO | ||||
E14.5(n = 12)b | total nuclei c | 2719; 363 | 2396; 338 * | −11.9 |
Foxi1+ nuclei | 797; 208 | 603; 116 * | −14.1 | |
Foxi1+ densityd | 290; 50 | 255; 51 | ns | |
E19 (n = 4) | total nuclei | 7645; 1344 | 5842; 525 | ns |
Foxi1+ nuclei | 1942; 372 | 1548; 69 | ns | |
Foxi1+ density | 241; 26 | 268; 31 | ns | |
Rbpj CKO | ||||
E15.5 (n = 6) | total nuclei | 4313; 332 | 1717; 158 ** | − 60.2 |
Foxi1+ nuclei | 667; 167 | 575; 96 | Ns | |
Foxi1+ density | 153; 31 | 335; 46 ** | + 118.4 |
Controls were Efnb2+/flox or Foxg1-Cre+;Rbpj+/flox
Refers to equally sized control and mutant samples
Refers to total number of DAPI+ nuclei within the domain of Foxi1 protein expression
Number of Foxi1+ nuclei per 1000 DAPI+ nuclei
Differences assessed by unpaired t-tests. Two-tailed values of
P < 0.05 and
P < 0.0001.
Non-significance (ns) was set at P > 0.05.