Figure 2.

Comparison of C1 domain, between the first and second conserved cysteine residues for different Simian Immunodeficiency Virus (SIV) lineages, Human Immunodeficiency Virus (HIV)-1 and HIV-2. The insertion of seven amino acids present in the SIVmus/mon/gsn lineage, SIVcpz, SIVgor and HIV-1 M, N, O, P is shown in red letters. In SIVs from guenons (Cercopithecus species), this domains ends in a glycine (highlighted in green box), while in all hominoid lineages the last amino acid residue of this domain is a highly conserved histidine (highlighted in yellow box). Dots indicate amino acid identity and dashes indicate gaps introduced to optimize the alignment.