Table 2.
Transfusion Characteristics
| Transfusion Variable | Factor 1a (Epo Study Drug) |
Factor 2 (Transfusion Threshold) |
|||
|---|---|---|---|---|---|
|
| |||||
| Epo 1 Regimen (n=38) |
Epo 2 Regimen (n=64) |
Placebo (n=98) |
Transfusion Threshold 7 g/dl (n=99) |
Transfusion Threshold 10 g/dl (n=101) |
|
|
| |||||
| Patients with at least one unit PRBCs required, n(%) |
23 (60.5) | 39 (60.9) | 63 (64.3) | 52 (52.5) | 73 (72.3) |
| Units of PRBCs required, n mean per patient (range) |
162 7 (1-15) |
195 5 (1-17) |
407 6.5 (1-22) |
243 4.7 (1-22) |
521 7.1 (1-21) |
| Given to keep hemoglobin above assigned threshold |
83 4.4 (1-7) |
109 3.8 (1-11) |
228 3.9(1-16) |
87 2.4(1-5) |
333 4.7 (1-16) |
| Given for active bleeding | 79 5.3 (1-11) |
82 3.2 (1-10) |
167 4.3(1-18) |
144 3.8(1-18) |
184 4.4 (1-12) |
| Given after acute care per clinical decision |
0 | 4 2 (2-2) |
8 2 (1-3) |
8 2 (2-2) |
4 2 (1-3) |
| Given in violation of protocol | 0 | 0 | 4 2 (2-2) |
4 2 (2-2) |
0 |
|
| |||||
| Time (hours) that hemoglobin was < 10 g/dl, median (25th-75th) |
8.3 * (.3-16.4) |
13.4 (3.5-39.7) |
18.9 (5.7-48.1) |
33.9 (4.0-60.8) |
10.5 ** (1.1-19.0) |
|
| |||||
| Time (hours) that hemoglobin was < 7 g/dl, median (25th-75th) |
0 (0-0) |
0 (0-0) |
0 (0-0.2) |
0.0 (0-.6) |
0.0 ** (0-0) |
a
Factors 1 and 2 include the same patients
*
different from Placebo group (p<0.05)
**
different from 7 g/dl threshold group (p<0.001)