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. 2014 Jul 28;211(8):1657–1672. doi: 10.1084/jem.20131800

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© 2014 Chu et al.

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Figure 9. — Parenteral immunization bypasses the requirement for EPO in DC activation and Th2 immunity. (A) WT or EPO-deficient mice received s.c. PN+CT or were kept naive, and draining inguinal LNs were analyzed 16–18 h later. Mice were immunized s.c. or i.p. weekly for 4 wk, or kept naive. (B) PN-IgE at wk 5. (C and D) Clinical responses after allergen challenge. (E) IL-4 production. Mean ± SEM, n = 3–8 from 2 experiments. ns, not significantly different.