Table 4. Serum PSA and PSA promoter genotype.
Genotype | n | Mean* (95% confidence interval) | P† | |
---|---|---|---|---|
rs266882 | GG | 253 | 11.25 (10.07-12.43) | 0.08 |
AG | 473 | 9.68 (8.94-10.49) | ||
AA | 241 | 9.58 (8.58-10.70) | ||
Dominant | GG | 253 | 11.25 (10.07-12.43) | 0.03 |
AG/AA | 714 | 9.68 (9.12-10.38) | ||
rs925013 | AA | 589 | 9.21 (8.58-9.87) | 0.003 |
AG | 315 | 11.02 (9.97-12.18) | ||
GG | 59 | 11.82 (9.49-14.88) | ||
Dominant | AA | 589 | 9.21 (8.58-9.87) | 0.0008 |
AG/GG | 374 | 11.13 (10.18-12.18) |
PSA levels were log-transformed and adjusted for age and geographic region. The values presented were back-transformed.
P values were obtained assuming a 2 df general test and dominant model, respectively.