Table 1.
Idiopathic short stature treated with GH, non-familial short stature (NFSS) & familial short stature (FSS)
| |
NFSS Mean (SD) |
FSS Mean (SD) |
Reference mean (SD) |
||
|---|---|---|---|---|---|
| Characteristic | Males (#47) | Females (#16) | Males (#21) | Females (#4) | Normal |
| Age start – yr |
11.96 (3.50) |
12.08 (1.39) |
11.96 (2.81) |
12.07 (0.88) |
|
| BA start – yr |
9.00 (3.20) |
9.39 (1.51) |
9.10 (2.91) |
10.30 (1.38) |
|
| GH stim peak mean |
12.4 |
10.8 |
13.1 |
14.8 |
>7 ng/ml |
| range – ng/ml |
7.04 to 28.0 |
7.0 to 19.8 |
7.1 to 38.5 |
8.8 to 20.9 |
>7 ng/ml |
| GH Freq Samp 12 |
2.53 (1.08) (#31) |
|
2.49 (1.46) (#11) |
|
M = 2.54 (0.84) |
| hr mean ng/ml |
|
1.78 (0.64) (#8) |
|
3.02 (#1) |
F = 1.96 (0.85) |
| SMC – U/ml |
0.79 (0.43) (#27) |
0.87 (0.22) (#6) |
1.09 (0.60) (#11) |
1.55 (0.04) (#2) |
T-I = 1.04 (0.66) |
| IGF-1 – ng/ml |
144 (101) (#19) |
166 (63) (#10) |
158 (69) (#11) |
205 (9) (#2) |
T-I = 109–485 |
| T-II = 174-512 | |||||
| Duration Rx – yr | 5.21 (2.69) | 3.59 (0.94) | 5.30 (2.30) | 3.17 (0.88) | |
Abbreviations: GH serum growth hormone, BA bone age, (#) number, M males, F females, T Tanner stage.