Table 11.
NFSS & FSS Adult Height Gain of Controls and Treated Subjects SDS (95% CI)
| |
|
GH Dosage |
Adult height gain of controls untreated |
NFSS to FSS Difference |
Adult height gain of treated subjects |
NFSS to FSS Difference |
|---|---|---|---|---|---|---|
| Published study | No. | mg/kg/wk | Mean SDS (95% CI) | SDS p | Mean SDS (95% CI) | SDS p |
| Wit et al. NFSS [9] |
36 |
0.32 to 0.14 |
0.8 (0.62 to 0.98) |
0.5 SDS p <0.01 |
1.50 (1.23 to 1.77) |
0.7 SDS p <0.05 |
| Wit et al. [9] FSS |
5 |
0.32 to 0.27 |
0.3 (-0.05 to 0.65) |
0.80 (0.06 to 1.54) |
||
| Albertsson-Wikland et al. NFSS [3] |
48 |
0.47 |
0.5 (0.23 to 0.77) |
0.6 SDS p <0.05 |
1.40 (1.17 to 1.63) |
0.5 SDS p < 0.05 |
| Albertsson-Wikland et al. [3] FSS |
14 |
0.47 |
-0.1 (-0.79 to 0.59) |
0.90 (0.44 to 1.36) |
||
| |
|
|
Adult height
|
|
Adult height gain
|
|
| Our Study NFSS (treated) |
63 |
0.32 (0.03) |
-0.56 (-0.72 to -0.40) |
0.52 SDS p < 0.01 | 2.06 (1.87 to 2.25) |
0.55 SDS p <0.001 |
| Our Study FSS (treated) | 25 | 0.32 (0.03) | -1.08 (-1.41 to -0.75) | 1.51 (1.24 to 1.78) |