Table 2.

Effects of atorvastatin on blood concentrations of lipids and hormones

	Control baseline	5-month treatment	3 months after withdrawal
Serum levels of lipids
Total cholesterol (g/L)	1.67 ± 0.08	1.27 ± 0.07***	1.71 ± 0.08
Triglycerides (g/L)	0.83 ± 0.06	0.73 ± 0.11	0.93 ± 0.14
HDL-C (g/L)	0.53 ± 0.03	0.52 ± 0.03	0.51 ± 0.03
LDL-C (g/L)	0.98 ± 0.07	0.57 ± 0.05***	0.98 ± 0.07
Serum levels of hormones
FSH (UI/L)	2.85 ± 0.30	2.87 ± 0.33	2.89 ± 0.30
LH (UI/L)	4.47 ± 0.54	5.00 ± 0.37	4.57 ± 0.35
Total testosterone (nmol/L)	22.71 ± 1.56	24.04 ± 1.99	22.81 ± 1.71

Data are presented as mean ± SEM. Seventeen normocholesterolaemic men received 10 mg/d atorvastatin during 5 months as described in Methods. The serum levels of total cholesterol, triglycerides, HDL-C, LDL-C, FSH, LH and total testosterone were measured before, during and 3 months after the end of treatment. ***indicates values significantly different from those obtained before treatment with p < 0.001.