TABLE 2.
Comparison of menarche and menstruation history by cohort and endometriosis diagnosis, ENDO Study, 2007 through 2009 (n = 600)
| Characteristic | Operative cohort n = 473 |
Population cohort n = 127 |
||
|---|---|---|---|---|
| Endometriosis n = 190 n (%) |
No endometriosis n = 283 n (%) |
Endometriosis n = 14 n (%) |
No endometriosis n = 113 n (%) |
|
| Menarche, y | ||||
| ≤11 | 37 (19.9) | 48 (17.3) | 2 (15.4) | 18 (16.5) |
| 12–13 | 87 (46.8) | 146 (52.5) | 5 (38.5) | 61 (56.0) |
| ≥14 | 62 (33.3) | 84 (30.2) | 6 (46.2) | 30 (27.5) |
| Mean (±SD) | 13.0 (1.8) | 12.8 (1.6) | 13.2 (1.5) | 12.7 (1.5) |
| No. of menstrual cycles in past 12 mo | ||||
| None | 5 (2.6) | 13 (4.6)a | 1 (7.1) | 4 (3.6) |
| 1–3 | 5 (2.6) | 20 (7.1) | 0 (0.0) | 4 (3.6) |
| 4–6 | 8 (4.2) | 23 (8.2) | 2 (14.3) | 11 (9.8) |
| 7–9 | 20 (10.6) | 17 (6.0) | 0 (0.0) | 10 (8.9) |
| 10–12 | 128 (67.7) | 158 (56.2) | 11 (78.6) | 72 (64.3) |
| ≥13 | 23 (12.2) | 50 (17.8) | 0 (0.0) | 11 (9.8) |
| Mean (±SD) | 11.0 (3.5) | 11.3 (8.5) | 10.1 (4.0) | 11.2 (11.1) |
| Average cycle length in past 12 mob | ||||
| <22 | 24 (13.2) | 54 (20.3) | 1 (8.3) | 5 (4.7) |
| 22–24 | 5 (2.7) | 10 (3.8) | 0 (0.0) | 7 (6.6) |
| 25–27 | 22 (12.1) | 27 (10.1) | 3 (25.0) | 24 (22.6) |
| 28–30 | 105 (57.7) | 139 (52.3) | 7 (58.3) | 54 (50.9) |
| 31–33 | 12 (6.6) | 9 (3.4) | 0 (0.0) | 4 (3.8) |
| ≥34 | 14 (7.7) | 27 (10.2) | 1 (8.3) | 12 (11.3) |
| Mean (±SD) | 28.1 (8.7) | 31.6 (31.7) | 27.4 (3.5) | 30.3 (11.1) |
| Mean (±SD) length of shortest cycle in past 12 mo, db | 18.2 (10.6) | 21.3 (29.6) | 30.5 (18.2) | 26.8 (10.9) |
| Mean (±SD) length of longest cycle in past 12 mo, db | 28.8 (22.7) | 34.2 (39.4)c | 37.7 (34.1) | 33.6 (15.2) |
| Few periods than normal in past 12 mo? | ||||
| No | 161 (85.2) | 236 (84.0) | 13 (92.9) | 88 (78.6) |
| Yes, no medications | 1 (0.5) | 4 (1.4) | 0 (0.0) | 1 (0.9) |
| Yes, medications | 27 (14.3) | 41 (14.6) | 1 (7.1) | 23 (20.5) |
| Periods in past 12 mo typical of last 5 y | ||||
| Yes | 83 (43.9) | 95 (33.9) | 4 (28.6) | 58 (52.3) |
| No; specify | 106 (56.1) | 185 (66.1) | 10 (71.4) | 53 (47.7) |
| More frequent | 29 (27.4) | 54 (29.2) | 1 (10.0) | 12 (22.6) |
| Less frequent | 17 (16.0) | 32 (17.3) | 3 (30.0) | 14 (26.4) |
| Heavier bleeding | 72 (67.9) | 102 (55.1) | 1 (10.0) | 22 (41.5) |
| Lighter bleeding | 24 (22.6) | 53 (28.6) | 7 (70.0) | 24 (45.3) |
| Bleeding more days | 56 (52.8) | 87 (47.0) | 2 (20.0) | 13 (24.5) |
| Bleeding fewer days | 20 (18.9) | 36 (19.5) | 2 (20.0) | 21 (39.6) |
| Pelvic pain >6 mo affecting normal function | ||||
| No | 106 (55.8) | 184 (65.2)d | 13 (92.9) | 102 (90.3) |
| Yes | 84 (44.2) | 98 (34.8) | 1 (7.1) | 11 (9.7) |
| Painful menses cramps >6 mob | ||||
| No | 91 (49.2) | 179 (66.8)e | 12 (92.3) | 98 (89.9) |
| Yes; specify duration, mo | 94 (50.8) | 89 (33.2) | 1 (7.7) | 11 (10.1) |
| <6 | 8 (6.8) | 6 (4.7) | 1 (50.0) | 2 (10.5) |
| 6–12 | 24 (20.3) | 31 (24.4) | 0 (0.0) | 1 (5.3) |
| 13–24 | 25 (21.2) | 20 (15.8) | 1 (50.0) | 3 (15.8) |
| >24 | 61 (51.7) | 70 (55.1) | 0 (0.0) | 13 (68.4) |
a
P = .0075;
b
Among women with ≥1 menstrual cycles in past 12 mo;
c
P = .07;
d
P = .0384;
e
P = .0002.
Peterson. Risk factors associated with endometriosis. Am J Obstet Gynecol 2013.