TABLE 5.
Risk factors for stages 3 and 4 endometriosis, ENDO Study, 2007 through 2009 (n = 339), sensitivity analysis
| Risk factor | Operative cohort | |
|---|---|---|
| Unadjusted OR (95% CI) | Adjusteda OR (95% CI) | |
| Sociodemographic | ||
| Age, y | 0.99 (0.95–1.03) | — |
| Above poverty level (yes/no)b | 2.70 (0.80–9.09) | 2.99 (0.87–10.3) |
| College educated (yes/no) | 1.77 (0.80–3.93) | 1.93 (0.86–4.31) |
| Reproductive history | ||
| Gravid (vs nulligravid) | 0.33 (0.18–0.60) | 0.27 (0.14–0.51) |
| Parous (vs nulliparous) | 0.26 (0.14–0.48) | 0.19 (0.10–0.37) |
| Infertility history (yes/no) | 4.90 (2.66–9.00) | 4.74 (2.57–8.75) |
| Age first consenting sex, y | 1.11 (1.03–1.18) | 1.11 (1.03–1.19) |
| Surgical indication for laparoscopy (pelvic pain vs other) | 4.44 (2.42–8.16) | 4.47 (2.39–8.38) |
| Menstruation (in past 12 mo) | ||
| Age at menarche, y | 1.09 (0.91–1.30) | 1.07 (0.90–1.29) |
| Mean no. of periodsc | 0.98 (0.93–1.04) | 0.99 (0.94–1.04) |
| Mean cycle length, dc | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) |
| Mean length shortest cycle, dc | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) |
| Mean length longest cycle, dc | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) |
| Dysmenorrhea (yes/no) | 3.61 (1.08–12.0) | 3.43 (1.02–11.5) |
| Pelvic pain (yes/no) | 1.63 (0.91–2.91) | 1.60 (0.89–2.87) |
| Body mass index, kg/m2 | 0.97 (0.93–1.01) | 0.97 (0.93–1.01) |
Cl, confidence interval; OR, odds ratio.
a
Adjusted for age (y) and site;
b
Based on 2007 HHS Poverty Guidelines accounting for numbers of persons in household for 48 contiguous states and District of Columbia;
c
Among women with ≥1 menstrual cycles in past 12 mo.
Peterson. Risk factors associated with endometriosis. Am J Obstet Gynecol 2013.