TABLE 6.
Risk factors for endometriosis in comparison to women with normal pelvis postoperatively, ENDO Study, 2007 through 2009 (n = 320), sensitivity analysis
| Risk factor | Operative cohort | |
|---|---|---|
| Unadjusted OR (95% CI) | Adjusteda OR (95% CI) | |
| Sociodemographic | ||
| Age, y | 0.96 (0.93–0.99) | — |
| Above poverty level (yes/no)b | 1.90 (0.95–3.80) | 2.38 (1.15–4.92) |
| College educated (yes/no) | 2.43 (1.39–4.24) | 2.62 (1.48–4.63) |
| Reproductive history | ||
| Gravid (vs nulligravid) | 0.22 (0.13–0.39) | 0.23 (0.13–0.42) |
| Parous (vs nulliparous) | 0.18 (0.11–0.31) | 0.18 (0.10–0.32) |
| Infertility history (yes/no) | 2.85 (1.64–4.97) | 2.91 (1.66–5.11) |
| Age first consenting sex, y | 1.07 (1.00–1.14) | 1.09 (1.02–1.16) |
| Surgical indication for laparoscopy (pelvic pain vs other) | 3.78 (2.36–6.05) | 3.76 (2.29–6.20) |
| Menstruation (past 12 mo) | ||
| Age at menarche, y | 1.04 (0.91–1.19) | 1.04 (0.91–1.19) |
| Mean no. of periodsc | 0.97 (0.93–1.02) | 0.98 (0.95–1.02) |
| Mean cycle length, dc | 1.00 (0.98–1.01) | 1.00 (0.98–1.01) |
| Mean length shortest cycle, dc | 1.00 (0.99–1.02) | 1.00 (0.98–1.02) |
| Mean length longest cycle, dc | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) |
| Dysmenorrhea (yes/no) | 3.11 (1.53–6.31) | 2.96 (1.43–6.13) |
| Pelvic pain (yes/no) | 1.82 (1.14–2.91) | 1.75 (1.08–2.82) |
| Body mass index, kg/m2 | 0.96 (0.93–0.99) | 0.96 (0.93–0.99) |
Analysis restricted to women reported to have normal pelvis following laparoscopy. Endometriosis defined as visualized disease.
Cl, confidence interval; OR, odds ratio.
a
Adjusted for age (y) and site;
b
Based upon 2007 HHS Poverty Guidelines accounting for numbers of persons in household for 48 contiguous states and District of Columbia;
c
Among women with ≥1 menstrual cycles in past 12 mo.
Peterson. Risk factors associated with endometriosis. Am J Obstet Gynecol 2013.