Table 1.
Summary data showing proximal colon histopathological score in mice treated with DSS
Proximal colon | Edema | Villi shortening | Ulceration | Immune cell infiltration |
---|---|---|---|---|
WT | 3.00±0.58 | 2.33±0.33 | 2.33±0.33 | 2.67±0.33 |
VIP−/− | 1.00±0.29* | 0±0** | 0±0** | 0.78±0.22* |
WT+vehicle | 2.80±0.39 | 2.20±0.53 | 2.30±0.54 | 2.90±0.38 |
WT+1 μM VIPHyb | 1.33±0.21* | 0.33±0.21** | 0.33±0.21*** | 1.50±0.22* |
WT+1 nM PG 97-269 | 1.67±0.33 | 0.83±0.40* | 0.83±0.40* | 1.67±0.33* |
p<0.05,
p<0.01,
p<0.001