Table 3.

Correlations between Aβ and Amylin in Plasma in Humans.

Diagnoses	Controls	Amnestic MCI	Alzheimer's disease
	N = 145	N = 16	N = 42
Age, year, Mean ± SD*	72.3 ± 8.0	75.7 ± 8.7	80.5 ± 8.1
MMSE, Mean ± SD*	27.1 ± 2.6	26.4 ± 2.5	22.2 ± 3.3
Log10 Amylin with Log10 Aß1-42	r = +0.06, p = 0.46	r = +0.73, p = 0.001	r = +0.52, p = 0.0004
Log10 Amylin with Log10 Aß1-40	r = +0.02, p = 0.83	r = +0.58, p = 0.02	r = +0.29, p = 0.06

Using ANOVA analysis, age and average Mini Mental State Exam (MMSE) scores in the subgroups of the controls, amnestic mild cognitive impairment (amnestic MCI) and Alzheimer's disease are compared.

^*p < 0.0001. Pearson analyses were performed to determine correlation coefficient between plasma Aβ40 or Aβ42 and amylin in different subgroups: the controls, amnestic MCI and Alzheimer's disease. p-values for statistical significance are shown.