Table 3.
Diagnoses | Controls | Amnestic MCI | Alzheimer's disease |
---|---|---|---|
N = 145 | N = 16 | N = 42 | |
Age, year, Mean ± SD* | 72.3 ± 8.0 | 75.7 ± 8.7 | 80.5 ± 8.1 |
MMSE, Mean ± SD* | 27.1 ± 2.6 | 26.4 ± 2.5 | 22.2 ± 3.3 |
Log10 Amylin with Log10 Aß1-42 | r = +0.06, p = 0.46 | r = +0.73, p = 0.001 | r = +0.52, p = 0.0004 |
Log10 Amylin with Log10 Aß1-40 | r = +0.02, p = 0.83 | r = +0.58, p = 0.02 | r = +0.29, p = 0.06 |
Using ANOVA analysis, age and average Mini Mental State Exam (MMSE) scores in the subgroups of the controls, amnestic mild cognitive impairment (amnestic MCI) and Alzheimer's disease are compared.
p < 0.0001. Pearson analyses were performed to determine correlation coefficient between plasma Aβ40 or Aβ42 and amylin in different subgroups: the controls, amnestic MCI and Alzheimer's disease. p-values for statistical significance are shown.