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. Author manuscript; available in PMC: 2014 Jul 29.
Published in final edited form as: Cancer Res. 2012 Apr 13;72(12):2937–2948. doi: 10.1158/0008-5472.CAN-11-3368

Table 4.

Factors influencing duration of response (TNTx ≥6 months) after Ad-ISF35 IDI

HRa (95% CI) P
No. of previous treatment (≤1) 0.1491 (0.04071–0.5464) 0.0041
ZAP-70 (≤20% positive cells) 0.6217 (0.1900–1.941) 0.4001
B2M (≤2.5 mg/L) 1.029 (0.3536–3.011) 0.9543
IgG levels (≤500 mg/dL) 1.799 (0.6586–5.830) 0.2266
Splenomegaly (≤5 cm) 1.974 (0.7330–6.671) 0.1589
LNP (total ≤70 cm2) 2.104 (0.6982–9.480) 0.1556

NOTE: Splenomegaly measured in cm below the right costal margin.

Abbreviations: B2M, (β2 microglobulin; LNP, bidimensional lymph node product.

a

HRs calculated with Kaplan–Meier analysis.