Table 1.
Proteins recruited into rRNA, histone mRNA, poly(A) mRNA and/or small regulatory RNA processing or biogenesis pathways
Protein | Protein Activity | rRNA | Histone mRNA | Poly(A) RNAs | Small Regulatory RNA | Refs |
---|---|---|---|---|---|---|
Eri1 | 3′–5′ exoribonuclease | + | + | miRNA, endo-siRNA | [4,5,9,17,18,26,28,58] | |
p68 | RNA helicase | + | Pri-miRNA | [70,71] | ||
p72 | RNA helicase | + | Pri-miRNA | [70,71] | ||
caDcr1 | Endonuclease | + | siRNA | [74] | ||
DGCR8 | dsRNA binding | + | Pri-miRNA | [72,78–80] | ||
Drosha | Endonuclease | + | Pri-miRNA | [83–85] | ||
Rrp6 | 3′–5′ exoribonuclease | + | + | + | Tailed mirtron | [75,76,86,87] |
Ars2 | RNA binding | + | + | miRNA | [81–84,97] | |
Zcchc11 | TUTase | + | Pre-miRNA, miRNA | [37–41,94] | ||
Dis3l2 | 3′–5′ exoribonuclease | + | Pre-let-7 | [91–93] | ||
PARN | Poly(A) exoribonuclease | + | Pre-miR-451 | [95] | ||
Triman | 3′–5′ exoribonuclease | priRNA, siRNAs | [96] |