Skip to main content
. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Top Curr Chem. 2014;343:1–32. doi: 10.1007/128_2013_481

Table 1.

Radical Addition to Chiral Glyoxylic Oxime Ethers.

graphic file with name nihms602654u1.jpg
Entry R1 Yielda drb
1 Et 80% 95:5
2 i-Bu 83% 97:3
3 i-Pr 80% 96:4
4 s-Bu 69%c >98:2
5 c-C6H11 86% 96:4
6 t-Bu 83% >98:2
7 AcO(CH2)4 41%d >98:2
8 Cl(CH2)4 15%d >98:2
a

Isolated yield.

b

dr = diastereomer ratio.

c

Obtained as 1:1 mixture of diastereomers.

d

Major product was ethyl addition.