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Additions of Alkyl Iodides to γ-Hydrazonoesters
| ||||
|---|---|---|---|---|
| entry | hydrazone | iodide R3I | product, yield | dr |
| 1 | 37a | i-PrI | 38a, >99% | 94:6 |
| 2 | 37b | 38b, 98% | 95:5 | |
| 3 | 37c | 38c, 96% | 99:1 | |
| 4 | 37d | 38d, 96% | 90:10 | |
| 5 | 37a |
|
39, 82% | -- |
| 6 |
|
40, 66% | 94:6 | |
| 7 |
|
41, 37% | 96:4 | |
| 8 |
|
42, 61% | 97:3 | |
| 9 |
|
43, 33% | 96:4 | |
| 10 |
|
44, 45% | 85:15 | |
