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. Author manuscript; available in PMC: 2014 Jul 29.
Published in final edited form as: Annu Rev Genet. 2010;44:113–139. doi: 10.1146/annurev-genet-051710-150955

Figure 2. Pathways and regulation at stalled replication forks.

Figure 2

PCNA modification regulates the choice of competing pathways for stalled replication fork recovery. A stalled fork triggers the DDR, which directly activates HR. The relationship between the DDR and cell cycle control to PCNA sumoylation/ubiquitylation has not been determined yet.