Table 1. Components of the Scribble complex in different species.
Drosophila | C. elegans | Mammals | ||||
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Mr (kDa) | Mr (kDa) | Mr (kDa) | Gene Symbol | |||
Scribble | 190 | LET-413 | 75 | Scrb1/Crib1/Vartul/hScrib | 250*/175 | SCRB1 |
Lgl | 127 | – | Lgl1 | 115 | LLGL1 | |
Lgl2 | 113 | LLGL2 | ||||
Lgl3/syntaxin-binding protein5 | 127 | LLGL3 | ||||
Lgl4/syntaxin-binding protein5-like | 130 | LLGL4 | ||||
Dlg | 107 | Dlg1 | 107 | SAP97/hDlg1 | 130*/100 | DLG1 |
PSD93/Chapsyn110 | 65 | DLG2 | ||||
SAP102/NE-Dlg | 90 | DLG3 | ||||
SAP90/PSD95 | 85 | DLG4 | ||||
LP-Dlg | 202 | DLG5 |
This apparent Mr was obtained by immunoblot analysis based on SDS-PAGE and the corresponding specific antibodies performed in our laboratory using rat testes as lysates.