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GI50 and MGM values of compound 16 g obtained for representative cell lines in the NCI-60 screening panel
| Cell Line | GI50 [μm][a] | Cell Line | GI50 [μm][a] |
|---|---|---|---|
| Leukemia CCRF-CEM | 0.0171 | Melanoma UACC-62 | <0.01 |
| Lung HOP-62 | 0.0295 | Ovarian OVCAR-3 | <0.01 |
| Colon HCT-116 | 0.0216 | Renal SN12-C | 0.056 |
| CNS SF-539 | 0.0102 | MGM | 0.033 |
[a] Results are the mean of three determinations. The MGM value (in italics) represents the mean concentration that caused 50 % growth inhibition in all 60 cell lines.
