Table 1.

Summary of physiological measurements between baseline and hypoxic conditions (shown as mean ± standard deviation over subjects). The baseline average is across the entire 5-min baseline normoxia period and the hypoxic average is the average across the last 5 min of the hypoxic period

	Baseline	Hypoxia	p
Spo2 (%)	98.5a	83.4 ± 6.8
Respiration rate (breaths/min)	13.2 ± 4.5	14.3 ± 3.7	0.05
Heart rate (beats/min)	66.6 ± 7.9	74.4 ± 8.7	<0.001
PETco2 (mmHg)	41.2 ± 2.8	39.8 ± 2.5	<0.001
PETo2 (mmHg)	116.6 ± 4.4	52.0 ± 3.8	<0.001

P_ETco₂, partial pressure of end-tidal carbon dioxide; P_ETo₂, partial pressure of end-tidal oxygen; S_po₂, blood oxygen saturation.

p values are derived from a paired t-test comparing baseline normoxia with hypoxic hypoxia.

^aAssumed from standard values.