Table 3.
Model parameters (confidence intervals of fitting) for R2* response to hypoxia
| R2*B (s–1) | R2*H (s–1) | R2*R (s–1) | kH (s–1) | kR (s–1) | δH (s) | δR (s) | |
|---|---|---|---|---|---|---|---|
| All grey matter | 30.33 | 31.48 | 30.04 | 0.0392 | 0.0921 | 24 | 12 |
| (30.31, 30.34) | (31.47, 31.49) | (30.03, 30.06) | (0.0333, 0.045) | (0.0744, 0.1098) | (21,26) | (10,13) | |
| Frontal lobe | 34.45 | 35.41 | 33.74 | 0.0577 | 0.1041 | 22 | 10 |
| (34.42, 34.48) | (35.40, 35.43) | (33.7173, 33.7703) | (0.0345, 0.0809) | (0.0701, 0.1382) | (17,27) | (8,12) | |
| Insula | 19.01 | 19.85 | 18.44 | 0.0239 | 0.0864 | 22 | 9 |
| (19.00, 19.02) | (19.84, 19.85) | (18.44, 18.45) | (0.0221, 0.0256) | (0.0796, 0.0932) | (20,24) | (8,9) | |
| Occipital lobe | 30.14 | 31.68 | 30.09 | 0.0091 | 0.0648 | 0 | 12 |
| (30.12, 30.16) | (31.67, 31.69) | (30.07, 30.11) | (0.0085, 0.0096) | (0.0547, 0.0749) | (–5, 5) | (10,14) | |
| Parietal lobe | 23.47 | 24.86 | 23.12 | 0.0135 | 0.0847 | 9 | 11 |
| (23.46, 23.48) | (24.85, 24.86) | (23.11, 23.13) | (0.0127, 0.0143) | (0.0755, 0.0939) | (6,12) | (10,11) | |
| Putamen | 31.84 | 32.58 | 31.80 | 0.1363 | 0.1449 | 32 | 20 |
| (31.81, 31.87) | (32.56, 32.59) | (31.77, 31.82) | (0.0377, 0.235) | (0.0182, 0.2717) | (28, 35) | (16,25) | |
| Temporal lobe | 33.77 | 35.33 | 33.45 | 0.0241 | 0.1114 | 13 | 10 |
| (33.73, 33.79) | (35.32, 35.34) | (33.42, 33.47) | (0.0208, 0.0274) | (0.0837, 0.1392) | (9,17) | (8,12) | |
| Thalamus | 21.36 | 22.97 | 20.95 | 0.0217 | 0.082 | 18 | 11 |
| (31.35, 21.37) | (22.96, 22,98) | (20.94, 20.96) | (0.0204, 0.0229) | (0.075, 0.0891) | (16,20) | (10,11) |
R2*B, baseline R2*; R2*H, equilibrium R2* during hypoxia; R2*R, recovery R2*; kH, rate constant in the transition to hypoxia; kR, rate constant in the return to normoxia; δH, delay in hypoxia response; δR, delay in response on return to normoxia (refer to Fig. 1).