Fig. 2.
Mice vaccinated with Qβ-16 L2(108–120) show variable levels of cross-protection from heterologous HPV PsV challenges. Two weeks after their last immunization, groups of mice were vaginally challenged with 107 IU HPV PsV, as described in Fig. 1C. Solid circles represent mice immunized with wild-type Qβ, empty circles represent mice immunized with Qβ-16 L2(108–120). Data points indicate the average radiance of individual mice and lines represent the geometric mean of each group. Data were analyzed by two-tailed, unpaired t-tests and p-values are listed.