Figure 4.

Nek6 influences cell cycle progression. (A) Nek6 overexpression promoted cell cycle progression from G₀/G₁ to G₂/M phase in Huh7 cells. (B) Percentage distribution of cell cycle. Data are presented as the mean ± SD of three independent experiments. ^**P<0.01 and ^***P<0.001, vs. the control. (C) Nek6 knockdown induced cell cycle arrest at the G₂/M phase in Hep3B cells. (D) Percentage distribution of cell cycle. Data are presented as the mean ± SD of three independent experiments. ^*P<0.05, vs. the control. Nek6, never in mitosis gene A-related kinase 6; NC, negative control; SD, standard deviation; siRNA, small interfering RNA; PI, propidium iodide.