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Combined effect of 1,25(OH)2D3 and carboplatin on cell cycle distribution. (A) G2/M cell cycle arrest in SKOV-3 cells treated with 1,25(OH)2D3 and carboplatin versus the untreated cells. */#P<0.05, vs. the vehicle controls. (B) Flow cytometric analysis: a, control group; b, 10-nM 1,25(OH)2D3 group; c, 40-mg/l carboplatin group; and d, combined treatment group. Similar results were obtained in all three experiments. 1,25(OH)2D3, 1,25-dihydroxyvitamin D3.
