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. 2014 Mar 7;5:e27958. doi: 10.4161/sgtp.27958

Table 1. GEFs and GAPs involved in cell adhesion and migration.

      GEF/GAP       Rac/Rho specificity       Name       Common synonyms       Force-regulated       References
      GEF       Rac       β-Pix       COOL-1, ArhGEF7       Yes86       41,42,68,86,103
      DOCK180       DOCK1       -       43,44,103
      Trio (N-term)       -       -       48-50
      Vav2       -       Yes132       53-55,132
      Tiam1       -       -       35,55,57,59,113
      α-Pix       COOL-2, ArhGEF6       -       65-67
      Asef2       -       -       114
      Rho       p190RhoGEF       Rgnef, ArhGEF28       -       76-78,99
      p115RhoGEF       Lsc, ArhGEF1       -       79,80
      LARG       ArhGEF12       Yes81       79,81,99
      GEF-H1       Lfc, ArhGEF2       Yes17,81       17,81,101
      Syx       Tech, PLEKHG5       -       94
      GAP       Rac       FilGAP       p73RhoGAP, ArhGAP24       Yes83       82-84,104,106
      ArhGAP22       -       Yes105       104,105
      RacGAP1       MgcRacGAP, CYK4       -       85,107
      Rho       p190RhoGAP       GRLF1, p190A, ArhGAP35       Yes131       27,28,69-72,99,131

GEFs and GAPs that are known to regulate RhoA or Rac1 during cell adhesion or migration are listed along with common synonyms. Those that have been shown to be regulated by tension are indicated.