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(A) Western blot analysis of PARP1 and XRCC2 protein expression in the five cell lines in response to treatment with AZD2281 and DDP. Protein expression of (B) PARP1 (C) cleaved PARP1 and (D) XRCC2 following treatment with AZD2281 and DDP. PARP, poly(ADP-ribose) polymerase; XRCC2, X-ray repair complementing defective repair in Chinese hamster cells 2; DDP, cisplatin; AZD2281, olaparib.
