Figure 3. Overview of the role of Rho GTPase signaling during late stages of infection. Rho GTPases are involved in late stages of infection for different viruses: projection formation, budding and release and exocytosis. For each process, the involvement of Cdc42, Rac1 and/or RhoA is indicated, in green if the Rho GTPase is upregulated or activated, in red when the Rho GTPase is downregulated or inhibited. Abbreviations: hepatitis c virus (HCV), Marek’s disease virus (MDV), human immunodeficiency virus (HIV-1), murid herpesvirus 68 (MHV-68), Epstein-Barr virus (EBV), vaccinia virus (VV), pseudorabies virus (PRV), herpes simplex virus 2 (HSV-2).