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(A) Microscopically, the lesions were composed of sheets of small atypical cells with little cytoplasm and large, round nuclei (stain, hematoxylin and eosin; magnification, ×100). Immunohistochemical EnVision™ staining revealed that the neoplastic cells were positive for (B) cytokeratins, (C) synaptophysin and (D) chromogranin A (magnification, ×100).
