FIGURE 2.

Sequence alignment of SBP2 from Homo sapiens, Danio rerio, Drosophila melanogaster, and the identified C. elegans SBP2. The reading frame of C. elegans SBP2 remains open upstream of the first Met, and translation from the first Ile completes the RBD (overlined in black). C. elegans SBP2 lacks the Sec incorporation domain (overlined in gray). The full-length D. melanogaster and C. elegans SBP2s are shown; in the case of vertebrate SBP2s, the first 400 amino acids (absent in invertebrate SBP2s) are not shown. Black blocks indicate positions which have a single, fully conserved residue. Dark gray and light gray blocks indicate conservation between groups of strongly or weakly similar properties, respectively. Numbers indicate the amino acid residue in the polypeptide chain.