Figure 4. CD4⁺CD69⁺ T cells are increased in mesenteric lymph nodes from Sirt2^−/− mice with DSS-induced colitis.

(A) Representative images of FACS analysis demonstrating TCRb⁺ cells (left), and their composition sorted by CD4 and CD69 staining (right). (B) The composition of MLNs is compared between Sirt2^+/+ and Sirt2^−/− mice; TCRb⁺, CD4⁺, CD4⁺CD69⁻, and CD4⁺CD69⁺ cells. n = 10/group. Results are expressed as the mean ± SEM. *P<0.05; **P<0.01; ***P<0.001.