Table 2.
The comparison of BMI, WHR, and glucose metabolic parameters among drug-naïve, antipsychotic-treated, and antipsychotic discontinuation patients with schizophrenia
| Drug-naïve patients n=70 |
Antipsychotic-treated patients n=33 |
Antipsychotic discontinuation patients n=28 |
F | P-value | Pairwise comparison (P-value)
|
|||
|---|---|---|---|---|---|---|---|---|
| Drug-naïve vs antipsychotic-treated | Antipsychotic-treated vs discontinuation | Drug-naïve vs antipsychotic discontinuation | ||||||
| BMI (kg/m2) | 19.63 (2.53) | 23.09 (3.92) | 22.28 (4.19) | 6.194 | 0.003 | 0.001 | 0.504 | 0.015 |
| Waistline (cm) | 70.42 (7.63) | 81.87 (9.35) | 78.92 (10.94) | 9.326 | 0.000 | 0.000 | 0.364 | 0.004 |
| WHR | 0.82 (0.06) | 0.89 (0.06) | 0.87 (0.09) | 2.743 | 0.068 | 0.022 | 0.247 | 0.158 |
| FPG (mmol/L) | 4.79 (0.71) | 5.11 (0.80) | 4.82 (0.62) | 1.306 | 0.274 | 0.182 | 0.139 | 0.743 |
| FINS (mU/L) | 8.49 (4.92) | 14.38 (9.23) | 12.84 (12.37) | 7.521 | 0.001 | 0.000 | 0.297 | 0.015 |
| C-peptide (nmol/L) | 0.45 (0.20) | 0.58 (0.23) | 0.57 (0.38) | 4.561 | 0.012 | 0.007 | 0.668 | 0.029 |
| IR | 1.83 (1.16) | 3.35 (2.73) | 2.90 (3.16) | 4.900 | 0.009 | 0.049 | 0.715 | 0.044 |
Note: Values are means (standard deviation) unless otherwise indicated.
Abbreviations: BMI, body mass index; FINS, fasting insulin resistance; FPG, fasting plasma glucose; IR, insulin resistance; WHR, waist–hip ratio.