Table 3.
The comparison of lipid metabolism parameters among three groups of patients with schizophrenia
| Drug-naïve patients n=70 |
Antipsychotic-treated patients n=33 |
Antipsychotic discontinuation patients n=28 |
F | P-value | Pairwise comparison (P-value)
|
|||
|---|---|---|---|---|---|---|---|---|
| Drug-naïve vs antipsychotic-treated | Antipsychotic-treated vs discontinuation | Drug-naïve vs antipsychotic discontinuation | ||||||
| TC (mmol/L) | 4.16 (0.77) | 4.51 (1.07) | 4.28 (1.07) | 0.226 | 0.798 | 0.997 | 0.588 | 0.579 |
| TG (mmol/L) | 1.12 (0.75) | 1.89 (1.08) | 1.37 (0.93) | 0.147 | 0.863 | 0.595 | 0.687 | 0.860 |
| HDL-C (mmol/L) | 1.29 (0.26) | 1.09 (0.24) | 1.12 (0.29) | 4.338 | 0.015 | 0.012 | 0.766 | 0.009 |
| LDL-C (mmol/L) | 2.50 (0.67) | 2.87 (1.04) | 2.67 (0.82) | 0.189 | 0.828 | 0.768 | 0.791 | 0.541 |
| aPOA1(g/L) | 1.20 (0.22) | 1.14 (0.19) | 1.14 (0.25) | 2.448 | 0.091 | 0.050 | 0.722 | 0.055 |
| aPOB100 (g/L) | 0.63 (0.15) | 0.74 (0.22) | 1.69 (5.35) | 0.076 | 0.927 | 0.770 | 0.703 | 0.940 |
Note: Values are means (standard deviation) unless otherwise indicated.
Abbreviations: aPOA1, apolipoprotein A1; aPOB100, apolipoprotein B100; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; WHR, waist–hip ratio.