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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2014 Jun 14;74:251–259. doi: 10.1016/j.yjmcc.2014.06.002

Figure 6.

Figure 6

Model of CL biosynthesis and remodeling in pediatric heart failure: Acyl-CoA-acyl-coenzyme A, CL-Cardiolipin, CDP-DAG-cytidinediphosphate-diacylglycerol, CDS-CDP-DAG synthase, CLS-CL synthase, CMP-cytidinemonophosphate, CoA-SH-coenzyme A (unconjugated), CTP-cytidinetriphosphate, DLCL-Dilyso-CL, FFA-free fatty acid, G3P-glycerol-3-phosphate, MLCL-monolyso-CL, MLCL-AT-MLCL acyltransferase, PG-phosphatidylglycerol, PGP-PG phosphate, PGPS-PG-P synthase, PGPP-PG-P phosphatase, Pi-inorganic phosphate, PLA2-phospholipase A2, TAZ-Tafazzin. Figure adapted from Chicco and Sparagna, 2007 [24].