Table 3.

Brain Data

Measures	Obese (n = 26) Mean ±SD	Lean (n = 27) Mean±SD	Effect Size	P
ICV volume (cc)	1198.98 ± 99.31	1209.62 ± 118.91	−0.10	0.73
Overall CSF volumea	31.83 ± 19.22	30.39 ± 10.82	−0.06	0.64
Hippocampal volume	2.96 ± 0.36	2.94 ± 0.38	0.11	0.71
PFC volume	313.73 ± 45.96	305.61 ± 42.32	0.43	0.14
OFC gray matter volume	27.52 ± 2.73	28.34 ± 2.84	−0.39	0.17
ACC gray matter volume	8.28 ± 1.47	8.53 ± 1.21	−0.18	0.52
Whole brain cortical thickness	2.46 ± 0.08	2.47 ± 0.07	−0.13	0.64
Total OFC cortical thickness	2.76 ± 0.14	2.83 ± 0.10	−0.55	0.05
Total ACC cortical thickness	2.83 ± 0.15	2.90 ± 0.16	−0.52	0.07

All brain data are residualized to the ICV volume. For ease of interpretation, raw values for the descriptive data are presented (volumes are expressed in cc and cortical thickness in mm³).

Normally distributed continuous variables were evaluated with the t-test (effect size Cohen’s d); otherwise,

^athe Mann-Whitney U test was used (effect size r: 0.1, small; 0.3, medium; 0.5, large).