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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Br J Dermatol. 2014 Jun 24;171(1):97–107. doi: 10.1111/bjd.12937

Figure 4. STAT2, STAT3 and ERK1/2 are significantly activated in lesional skin compared to uninvolved skin.

Figure 4

6mm punch skin biopsies were snap-frozen, pulverized and diluted to 1mg/ml total protein before analysis with Bio-Rad human phosphoprotein multiplex kits. Tissue levels of phospho-ERK1/2 (a) and phospho-GSK3a/b (c) were suppressed on days 1 and 7 after treatment with etanercept. Bars, mean fluorescence ± SEM, n=5. Statistical significance determined with paired t-test and indicated as ** p<0.01 and * p<0.05.