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. 2014 May 31;38(8):1671–1676. doi: 10.1007/s00264-014-2374-2

Table 2.

IL-1B gene polymorphisms among osteosarcoma patients and controls

Genotype Cases n (%) Controls n (%) OR (95 % CI) P value
−31 TT 60 (50.0) 50 (41.7) 1.00 (reference)
−31 TC 50 (41.7) 49 (40.8) 0.85 (0.49,1.47) 0.56
−31 CC 10 (8.3) 21 (17.5) 0.40 (0.17,0.92) 0.03
−31 T allele frequency 170 (70.8) 149 (62.1) 1.00 (reference)
−31 C allele frequency 70 (29.2) 91 (37.9) 0.67 (0.46,0.99) 0.04
−511 CC 59 (49.2) 52 (43.3) 1.00 (reference)
−511 CT 52 (43.3) 48 (40.0) 0.96 (0.56,1.64) 0.87
−511 TT 9 (7.5) 20 (16.7) 0.40 (0.17,0.95) 0.04
−511 C allele frequency 170 (70.8) 152 (63.3) 1.00 (reference)
−511 T allele frequency 70 (29.2) 88 (36.7) 0.71 (0.49,1.04) 0.08
+3954 CC 77 (64.2) 79 (65.8) 1.00 (reference)
+3954 CT 30 (25.0) 32 (26.7) 0.96 (0.53,1.73) 0.90
+3954 TT 13 (10.8) 9 (7.5) 1.48 (0.60,3.67) 0.40
+3954 C allele frequency 184 (76.7) 190 (79.2) 1.00 (reference)
+3954 T allele frequency 56 (23.3) 50 (20.8) 1.16 (0.75,1.78) 0.51

OR odds ratio, CI confidence interval