Table 2.
IL-1B gene polymorphisms among osteosarcoma patients and controls
| Genotype | Cases n (%) | Controls n (%) | OR (95 % CI) | P value |
|---|---|---|---|---|
| −31 TT | 60 (50.0) | 50 (41.7) | 1.00 (reference) | |
| −31 TC | 50 (41.7) | 49 (40.8) | 0.85 (0.49,1.47) | 0.56 |
| −31 CC | 10 (8.3) | 21 (17.5) | 0.40 (0.17,0.92) | 0.03 |
| −31 T allele frequency | 170 (70.8) | 149 (62.1) | 1.00 (reference) | |
| −31 C allele frequency | 70 (29.2) | 91 (37.9) | 0.67 (0.46,0.99) | 0.04 |
| −511 CC | 59 (49.2) | 52 (43.3) | 1.00 (reference) | |
| −511 CT | 52 (43.3) | 48 (40.0) | 0.96 (0.56,1.64) | 0.87 |
| −511 TT | 9 (7.5) | 20 (16.7) | 0.40 (0.17,0.95) | 0.04 |
| −511 C allele frequency | 170 (70.8) | 152 (63.3) | 1.00 (reference) | |
| −511 T allele frequency | 70 (29.2) | 88 (36.7) | 0.71 (0.49,1.04) | 0.08 |
| +3954 CC | 77 (64.2) | 79 (65.8) | 1.00 (reference) | |
| +3954 CT | 30 (25.0) | 32 (26.7) | 0.96 (0.53,1.73) | 0.90 |
| +3954 TT | 13 (10.8) | 9 (7.5) | 1.48 (0.60,3.67) | 0.40 |
| +3954 C allele frequency | 184 (76.7) | 190 (79.2) | 1.00 (reference) | |
| +3954 T allele frequency | 56 (23.3) | 50 (20.8) | 1.16 (0.75,1.78) | 0.51 |
OR odds ratio, CI confidence interval