Table 3.

Stratification analysis of IL-1B gene polymorphisms among osteosarcoma patients

Variable	Cases	−31 TT		−31 TC		−31 CC		−511 CC		−511 CT		−511 TT		+3954 CC		+3954 CT		+3954 TT
		n	P	n	P	n	P	n	P	n	P	n	P	n	P	n	P	n	P
Enneking stage	120	60		50		10		59		52		9		77		30		13
I	9	5	0.86	3	0.75	1	0.79	4	0.87	4	0.97	1	0.72	6	0.94	2	0.88	1	0.98
II	56	25	0.69	26	0.71	5	0.90	27	0.95	25	0.92	4	0.94	35	0.92	15	0.85	6	0.98
III	55	30	0.75	21	0.78	4	0.82	28	0.90	23	0.91	4	0.96	36	0.94	13	0.88	6	0.99
Tumour location	120	60		50		10		59		52		9		77		30		13
Extremities	91	46	0.96	37	0.92	8	0.91	45	0.98	39	0.97	7	0.96	60	0.90	22	0.92	9	0.84
Other	29	14	0.92	13	0.85	2	0.81	14	0.96	13	0.93	2	0.92	17	0.79	8	0.83	4	0.69
Histological type	120	60		50		10		59		52		9		77		30		13
Osteoblastic	38	19	1.00	16	0.98	3	0.94	18	0.91	17	0.92	3	0.94	25	0.93	9	0.90	4	0.96
Chondroblastic	41	20	0.94	17	0.99	4	0.80	20	0.98	18	0.97	3	0.97	26	0.97	10	0.95	5	0.83
Fibroblastic	15	7	0.89	7	0.82	1	0.84	8	0.86	6	0.88	1	0.91	10	0.93	4	0.91	1	0.65
Mixed	26	14	0.84	10	0.85	2	0.92	13	0.96	11	0.95	2	0.98	16	0.91	7	0.88	3	0.93
Tumor metastasis	120	60		50		10		59		52		9		77		30		13
Yes	55	28	0.95	23	0.99	4	0.82	28	0.90	23	0.91	4	0.96	35	0.98	14	0.96	6	0.99
No	65	32	0.95	27	0.99	6	0.85	31	0.91	29	0.92	5	0.97	42	0.98	16	0.96	7	0.99
Family history of cancer	120	60		50		10		59		52		9		77		30		13
Yes	11	4	0.60	6	0.61	1	0.94	5	0.89	5	0.93	1	0.86	7	0.99	3	0.90	1	0.87
No	109	56	0.91	44	0.90	9	0.99	54	0.97	47	0.98	8	0.97	70	0.99	27	0.98	12	0.97