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. 2014 Jul 30;34(31):10453–10458. doi: 10.1523/JNEUROSCI.3336-13.2014

Figure 3.

Figure 3.

Loss of αCGRP does not affect saccadic eye movement main sequence relationships or extraocular motor endplate densities. A, Fast phase main sequence relationships are not affected by the loss of αCGRP (compare αCGRP(−/−) (red) and αCGRP(+/+) (blue)). Inset, Nystagmus quick phase (arrow). B–E, Extraocular lateral rectus motor endplates stained for CGRP and ChAT (B, C), and αBTX (D, E), with only CGRP reactivity absent in αCGRP(−/−) mice (C, E). Scale bars, 10 μm. The density and structure of extraocular motor endplates are similar qualitatively between αCGRP(+/+) (B, D) and (−/−) animals (C, E). F, Numbers of αBTX-labeled motor endplates per 100 μm2 are not affected by the loss of αCGRP (n = 3 animals/group; 2 males/1 female/group; 10 fields/animal).