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. 2014 Jul 19;21(1):64. doi: 10.1186/s12929-014-0064-4

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Copyright © 2014 Chou et al.; licensee BioMed Central

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The metabolites of MTA cycle are affected byDADI1. (A) Four metabolites, Methionine, SAM, MTA and Methionine sulfoxide, were observed to be rescued in Dadi1 mutant ovaries by methionine addition. (B) Under the restricted diet condition, the metabolites of the methyl cycle and MTA cycle were dramatically changed in Dadi1 mutant ovaries. The raw data of metabolites are displayed below the picture. The results represent the means ± SD of three experiments. *P < 0.05, **P < 0.01 and N.S. indicates no significance.