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. Author manuscript; available in PMC: 2015 Aug 28.
Published in final edited form as: Cancer Lett. 2014 May 16;351(1):134–142. doi: 10.1016/j.canlet.2014.05.013

Figure 2.

Figure 2

Comparative expression of miR-146a (A) and EGFR (B) in the pancreata of K-Ras (K), Pdx1-Cre (C), K-Ras;Pdx1-Cre; (KC), and K-Ras;Pdx1-Cre;INK4a/Arf (KCI) mouse. There was a significant down-regulation in the expression of miR-146a in KC and KCI pancreata (tumors) compared to either K or C pancreata (normal pancreas). In contrast, the expression of EGFR was significantly up-regulated in KC and KCI tumors. The miR-146a expression was normalized using RNU48 miRNA and EGFR expression was normalized using GAPDH mRNA. P values represent comparison between K/C and KC/ KCI and were found to be significant (*) and less than 0.05.