Table 4.
Correlations between survival analysis and clinical parameters and expression of various HDACs
| Mean survival (mo) ± SD | p-valuea | |||
|---|---|---|---|---|
| Sex | M | F | ||
| 67.754 ± 6.707 | 63.987 ± 6.867 | 0.941 | ||
| Age | ≤45 | ≥46 | ||
| 70.203 ± 9.970 | 62.865 ± 5.602 | 0.328 | ||
| Sites | Nodal | Extranodal | ||
| 55.531 ± 6.906 | 72.134 ± 6.359 | 0.132 | ||
| HDACs | Low | High | ||
| 2 | Nucleus | 75.269 ± 7.571 | 58.715 ± 5.793 | 0.232 |
| 4 | Nucleus | 61.845 ± 6.511 | 71.074 ± 6.521 | 0.225 |
| Cytoplasm | 62.171 ± 8.017 | 67.174 ± 5.579 | 0.382 | |
| 5 | Nucleus | 65.602 ± 10.827 | 64.001 ± 5.069 | 0.765 |
| Cytoplasm | 62.437 ± 7.151 | 66.675 ± 6.526 | 0.800 | |
| 6 | Nucleus | 63.646 ± 5.806 | 64.246±8.166 | 0.834 |
| Cytoplasm | 68.488 ± 11.110 | 66.641 ± 5.536 | 0.909 | |
| Sites and HDACs | Nodal and 2NHb | Others | ||
| 50.357 ± 7.652 | 74.564 ± 5.812 | 0.018 | ||
| Nodal and 4NLc | Others | |||
| 50.316 ± 7.377 | 72.230 ± 5.733 | 0.092 | ||
| Nodal and 2NH & 4NLd | Others | |||
| 43.233 ± 8.145 | 74.263 ± 5.307 | 0.006 | ||
a. Log Rank
b. Nodal lymphoma cases showing high nuclear expression of HDAC2.
c. Nodal lymphoma cases showing low nuclear expression of HDAC4.
d. Nodal lymphoma cases showing high nuclear expression of HDAC2 but low nuclear expression of HDAC4.