Appendix Table 3. Risk Discrimination and Reclassification at 10 Years, by Method of AF Diagnosis^*

Variable	Study ECG (n = 70)		Discharge Coding (n = 138)
	Score (95% CI)	P Value	Score (95% CI)	P Value
C-statistic
Framingham	0.72 (0.65–0.76)	1.00 (reference)	0.62 (0.55–0.65)	1.00 (reference)
PAC	0.77 (0.72–0.81)	0.142†	0.66 (0.60–0.69)	0.28†
Framingham and PAC	0.82 (0.76–0.85)	<0.001†	0.69 (0.63–0.71)	0.001†
NRI	26.9 (12.2–41.6)	<0.001	13.9 (2.8–25.0)	0.014
IDI	7.9 (5.2–10.6)	<0.001	2.3 (1.2–3.4)	<0.001

AF = atrial fibrillation; ECG = electrocardiogram; IDI = integrated discrimination improvement; NRI = net reclassification improvement; PAC = premature atrial contraction.

^*At 10-y follow-up, 70 of the 208 AF diagnoses had been made by using study ECGs and 138 by hospital coding.

^†For comparison of the designated model c-statistic with the Framingham model c-statistic in the same AF diagnosis stratum.