Skip to main content
. 2014 Jul 7;111(29):10726–10731. doi: 10.1073/pnas.1320290111

Fig. 2.

Fig. 2.

Altered phenotype of Fezf2-expressing cells in adults. (A) Immunohistochemistry for Fezf2-EGFP, tdTomato, and GAD67 analyzed 4 wpi of the viral mix in adult SVZ (n = 10 mice). Open arrowheads indicate control tdTomato+/GAD67+ cells. The filled arrowhead indicates a typical oversized Fezf2+/GAD67− cell. (Scale bars: 20 μm.) (B) High magnification of a Fezf2 oversized neuron with a larger body size (14.45 μm) than control granule cells (9.78 μm). (Scale bars: 20 μm.) (C) Frequency distribution of cell body size of control and Fezf2 cells (bin width = 0.5 μm; ***P < 0.001, K-S test). (D) Whiskers graph for control and Fezf2 neurons subdivided in GAD67+ and GAD67− (one-way ANOVA; ***P < 0.001, Bonferroni multiple comparison post hoc test). (E) Stacked bar graph showing that most oversized (os) Fezf2+ cells lost their GABAergic phenotype (P < 0.0001, Fisher’s exact test).