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. 2014 Jul 30;8:223. doi: 10.3389/fnins.2014.00223

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Copyright © 2014 Castellazzi, Palesi, Casali, Vitali, Sinforiani, Wheeler-Kingshott and D'Angelo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Global cerebellar alterations in AD and MCI. For each RSNs and for each contrast (AD < HC, AD > HC, MCI < HC, and MCI > HC), the histograms show the global changes occurring in the cerebellum C(rgFC) in AD (A) and in MCI (B). For each RSN, the set of histograms shows: (1) the global changes of the rgFC index in the cerebellum (C), (2) the contribution to the rgFC in the cerebellum given by the spatial extension of the clusters of functional alteration (N_tstatFC/N_RSN), (3) the contribution of the magnitude extension of the cerebellar functional alteration [meanFC(C)_Pwith p = MCI or AD, normalized for the to the meanFC(C)_HC].