Table 2.

Summary of the dental characteristics in cardio-facio-cutaneous syndrome (CFC).

Dental Findings	CFC			General Populationb	p-valuec
	Affected	Total Examineda	%	%
Malocclusion
Vertical
Open bite	10	27	37	3	0.0001*
Deep bite	5	27	19	49	0.0001*
Transverse
Posterior crossbite	4	21	19	9	0.032*
Anterior/Posterior/Sagittal
Molar relationship
Class I	7	13	54	41	0.089
Class II	6	13	46	53	0.396
Class III	0	13	0	6	0.029*
Arch perimeter
Crowding	8	32	25	60	0.0001*
Spacing	7	32	22	N/Ad
Dental development
Missing teeth	1	31	3	N/A
Supernumerary teeth	0	31	0	N/A
Delayed development	0	2	0	N/A
Delayed eruption	4	32	13	N/A
Hard tissue
High-arched palate	16	20	80	N/A
Soft tissue
Frenal attachment
High	13	21	62	N/A
Low	8	21	38	N/A
Gingival hyperplasia	1	31	3	N/A
Pathology
Caries present at exam	7	28	25	N/A
History of caries	4	7	57	N/A
Habits
Tongue thrusting	7	31	23	N/A
Open mouth posture	9	32	29	N/A
Bruxism	3	31	10	N/A

^aNumber of CFC individuals examined for each dental characteristic since dental exams not completed on every CFC individual in the cohort

^bPrevalence of dental characteristic in general population as determined by the NHANESIII survey (10)

^cComparison of incidence of dental characteristic in CFC cohort compared to general population using the Fisher’s exact test with 2-tailed p-value

^*significant p-value<0.05

^dN/A Data not available